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What You Should "Realize" About CBN
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Written by David Nadel
CBN has been gaining attention for its unique properties and potential benefits.
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Realize featured - Best CBD Drinks for 2022
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Written by Tom Pavlica
Geijo Magazine recently included Realize Hemp Drinks in their Best CBD Drinks for 2022 article. They wrote:
"It’s the ultimate CBD drink if you’re looking to achieve light euphoria and improve your moods. The drink is delicious and refreshing"
Read the full article on ShopGeijo.com HERE.
High TImes Hemp Cup 2022 - First Place Edibles: Gummies, Pow Pow OG Kush Blood Orange Live Resin
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Written by Tom Pavlica
High Times Hemp Cup: People's Choice 2022 - First Place Edibles: Gummies, Pow Pow OG Kush Blood Orange Live Resin
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High TImes Hemp Cup 2022 - First Place Edibles: Non-Gummies, Realize Citrus-Mango Drink Mix
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Written by Tom Pavlica
High TImes Hemp Cup 2022 - First Place Edibles: Non-Gummies, Realie Citrus-Mango Drink Mix
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MCOA Subsidiary cDistro Signs Distribution Agreement with Award Winning Realize Hemp Drinks
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Written by Tom Pavlica
MCOA Subsidiary cDistro Signs Distribution Agreement with Award Winning Realize Hemp Drinks
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New Realize Product Review from Selena Renee'
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Written by Tom Pavlica
Selena Renee' YouTube video review for Realize Drink Mix Citrus-Mango flavor and Pow Pow D8 Infused Sugar HERE.
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Hemp Hangover Help
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Written by Tom Pavlica
Hangovers from alcohol are not fun. Realize Drink Mix may or may not help, you decide for yourself.
Shop our products HERE
NEW Flavor Alert! Citrus-Mango with 10mg THC
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Written by Tom Pavlica
NEW FLAVOR!
Citrus-Mango with 10mg THC
Tangy tangerine and mango flavors combined with 10MG THC and 50MG CBD to give an immersive full body high.
Award Winning, Realize Raspberry Drink Mix - Most Innovative CBD Product
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Written by Tom Pavlica
Most Innovative CBD Product Award
Realize Hemp Drinks - Raspberry Drink Mix
USA CBD Expo, Chicago, October 2021
Dr Mike Heller to speak at the USA CBD Expo Chicago October 2021
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Written by Tom Pavlica
Cofounder Dr Mike Heller to speak at the USA CBD Expo 10/28 - 10/30.
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Realize featured Best CBD Drinks for 2021
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Written by Luke Dickinson
Geijo Magazine recently included Realize Hemp Drinks in their Best CBD Drinks for 2021 article. They wrote: "it’s the ultimate CBD drink if you’re looking to achieve light euphoria and improve your moods. The drink is delicious and refreshing"
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Realize Featured in Posh Lifestyle & Beauty Blog
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Written by Tom Pavlica
The Posh Lifestyle and Beauty Blog included our Realize Raspberry Drink Mix in their May 2021 CBD shopping guide!
Link to the May 2021 CBD shopping guide: https://www.poshbeautyblog.com/health/2021/5/25/cbd-shopping-guide-may-2021?rq=cbd
CBD Scouts, Raspberry Drink Mix Product Review
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Written by Tom Pavlica
CBD Scouts review Realize Raspberry Drink Mix for taste, effect, bioavailability and more.
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Consumers might be wasting money buying certain CBD products, here’s why
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Written by Michael Heller
3 Things to look for when buying a CBD product:
- Keywords on a company’s website or product packaging such as: enhanced absorption, improved bioavailability, fast-acting, liposomal, micelle, nano or water-soluble.
- Validated studies that measure the absorption of CBD or other cannabinoids. An example can be found here.
- A Certificate of Analysis (COA) that confirms the amount of CBD or other cannabinoids in the product. An example can be found here.
Realize Featured on Retailmenot
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Written by Tom Pavlica
Realize Featured on Retailmenot
Realize was featured in an article from Retailmenot on August 7.
See below for the text version and at the bottom a link to the article.
The 11 Best National CBD Day Deals HEALTH · August 7, 2020 · By Tazi Phillips
Click the link for the full article: https://www.retailmenot.com/blog/national-cbd-day-deals.html
Considerations when choosing emulsions for infused cannabis or hemp products
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Written by Michael Heller
Considerations when choosing emulsions for infused cannabis or hemp products
Bioavailability: Emulsions will generally increase the bioavailability of cannabinoids; however, the degree of how well they improve bioavailability will vary for different emulsion systems used. Ingredient list: Many cannabis emulsions are made using synthetic ingredients that may be prohibitive for products that require a clean label. However, some emulsions such as Realize TM emulsion delivery system can be made from all-natural and organic ingredients.
Flavor profile: Many cannabis emulsions are extremely bitter and use chemicals that impart a soapy taste into the infused product. However, few systems exist that mask bitterness and are virtually tasteless. The RealizeTM emulsion delivery system was designed to mask the bitter taste of cannabinoids.
Shelf life: Not all emulsions are stable, and hence, they will degrade overtime. This instability can cause issues for products such as RTD beverages that require a long shelf life and are prone to oil separation. Choosing the right emulsion system that has sufficient stability and product compatibility is essential.
Cost: Emulsions can be expensive to manufacture and difficult to scale up making them cost prohibitive for certain products.
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Bioavailability: Emulsions will generally increase the bioavailability of cannabinoids; however, the degree of how well they improve bioavailability will vary for different emulsion systems used. Ingredient list: Many cannabis emulsions are made using synthetic ingredients that may be prohibitive for products that require a clean label. However, some emulsions such as Realize TM emulsion delivery system can be made from all-natural and organic ingredients.
Flavor profile: Many cannabis emulsions are extremely bitter and use chemicals that impart a soapy taste into the infused product. However, few systems exist that mask bitterness and are virtually tasteless. The RealizeTM emulsion delivery system was designed to mask the bitter taste of cannabinoids.
Shelf life: Not all emulsions are stable, and hence, they will degrade overtime. This instability can cause issues for products such as RTD beverages that require a long shelf life and are prone to oil separation. Choosing the right emulsion system that has sufficient stability and product compatibility is essential.
Cost: Emulsions can be expensive to manufacture and difficult to scale up making them cost prohibitive for certain products.
Reducing onset time of cannabinoids
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Written by Michael Heller
Reducing onset time of cannabinoids
An interesting finding from the PK Oral CBD study is that the emulsion delivery system achieved a higher plasma concentration of CBD (342 ng/ml) in 15 minutes compared to the maximum plasma concentrations achieved for CBD without a delivery system (26 ng/ml at 60 minutes) as well as CBD in a lipid delivery system (134 ng/ ml at 60 minutes).
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An interesting finding from the PK Oral CBD study is that the emulsion delivery system achieved a higher plasma concentration of CBD (342 ng/ml) in 15 minutes compared to the maximum plasma concentrations achieved for CBD without a delivery system (26 ng/ml at 60 minutes) as well as CBD in a lipid delivery system (134 ng/ ml at 60 minutes).
How do emulsions improve bioavailability?
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Written by Michael Heller
How do emulsions improve bioavailability?
O/W emulsions are dispersions of oil droplets in an aqueous solution that are stabilized against separation by emulsifiers creating micelles or liposomes. Micelles are small particles that have a hydrophobic (water repelling) core surrounded by a hydrophilic (water compatible) shell. Liposomes are vesicles having an aqueous core surrounded by a lipid bi-layer with a hydrophobic interior and a hydrophilic exterior.
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O/W emulsions are dispersions of oil droplets in an aqueous solution that are stabilized against separation by emulsifiers creating micelles or liposomes. Micelles are small particles that have a hydrophobic (water repelling) core surrounded by a hydrophilic (water compatible) shell. Liposomes are vesicles having an aqueous core surrounded by a lipid bi-layer with a hydrophobic interior and a hydrophilic exterior.
What happens when CBD is ingested without a delivery system?
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Written by Michael Heller
What happens when CBD is ingested without a delivery system?
When ingested, CBD has an extremely low bioavailability compared to the lipid delivery system and emulsion delivery systems
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When ingested, CBD has an extremely low bioavailability compared to the lipid delivery system and emulsion delivery systems
How can cannabis oral bioavailability be increased?
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Written by Michael Heller
How can cannabis oral bioavailability be increased?
It is possible to increase the oral bioavailability of cannabinoids by using drug delivery systems that promote solubilization.
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It is possible to increase the oral bioavailability of cannabinoids by using drug delivery systems that promote solubilization.
What causes the low oral bioavailability of cannabinoids?
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Written by Michael Heller
What causes the low oral bioavailability of cannabinoids?
Cannabinoids are lipophilic (fat soluble) and have low aqueous solubility [8, 9]. Lipophilic drugs with low solubility, such as cannabinoids often have low oral bioavailability [10]. A deeper look at the body’s digestive system reveals that there is an unstirred water layer (UWL) that lines the gastrointestinal tract (GIT). The UWL acts as a barrier to the absorption of lipophilic materials such as cannabinoids. Thus prior to reaching the absorptive surfaces of the GIT a cannabinoid must become water dispersible allowing it to permeate the UWL. Naturally this process of cannabinoid solubilization is inefficient leading to low oral bioavailability.
Businesses can purchase our water soluble CBD powder in bulk at: realizeinside.com
Consumers can buy our CBD products at: shoprealize.com/collections/all
Infused products have low bioavailability
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Written by Michael Heller
Infused products have low bioavailability
Cannabis edibles and oral dosage forms suffer from low bioavailability of cannabinoids. Cannabinoids are the active ingredients found in the plant and it's extracts. When taken orally only 4%-12% of the total cannabinoids consumed reach the bloodstream [1]. In comparison smoking cannabis can reach a bioavailability above 50% within minutes of inhalation [2-5]. Furthermore, the poor bioavailability of cannabinoids results in delayed onset; effects are typically felt between 60 to 120 minutes before [6].
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Cannabis edibles and oral dosage forms suffer from low bioavailability of cannabinoids. Cannabinoids are the active ingredients found in the plant and it's extracts. When taken orally only 4%-12% of the total cannabinoids consumed reach the bloodstream [1]. In comparison smoking cannabis can reach a bioavailability above 50% within minutes of inhalation [2-5]. Furthermore, the poor bioavailability of cannabinoids results in delayed onset; effects are typically felt between 60 to 120 minutes before [6].
Why is bioavailability important for cannabis infused products?
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Written by Michael Heller
Why is bioavailability important for cannabis infused products?
Bioavailability directly influences the effects of cannabis infused products impacting their time of onset, intensity and duration. Designing products with bioavailability in mind aids in creating optimal dosages while minimizing any unwanted side effects.
What is bioavailability?
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Written by Michael Heller
Bioavailability is the proportion and rate a drug or active ingredient enters the bloodstream. Once in the bloodstream it can access the site of action and illicit a physiological response.
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Nano CBD Ingredients Drive Realize Wellness Products
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Written by Tom Pavlica
Water soluble nano CBD is what drives Realize wellness products.
https://www.youtube.com/watch?v=_CQSZRmP_q0
Realize Wellness Social Networks
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Written by Tom Pavlica
Stay in touch with us on social media!
Facebook: https://www.facebook.com/realizeinside
Instagram: https://www.instagram.com/realizewellness/
Youtube: https://www.youtube.com/channel/UCtoJ0ygc3TEYfOVtGs2odVA?view_as=subscriber
- Team Realize Wellness
If I use CBD will I fail a drug test?
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Written by Tom Pavlica
I get this question quite frequently, here's a quick answer for you...
First, it is important to...
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This product is not for use by or sale to persons under the age of 21. This product should be used only as directed on the label. It should not be used if you are pregnant or nursing. Consult with a physician before use if you have a serious medical condition or use prescription medications. A Doctor’s advice should be sought before using this and any supplemental dietary product. All trademarks and copyrights are the property of their respective owners and are not affiliated with nor do they endorse this product. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. By using this site you agree to follow the Privacy Policy and all Terms & Conditions printed on this site. Void Where Prohibited By Law.
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